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SKLDB LACTOBACILLUS REPOSITORY
自1996年起,采集来自保加利亚、中国西藏、新疆等传统农牧业发达地区的样品500余份,包括自于健康人体生物标本(唾液、母乳、粪便)、传统发酵食品(马奶酒、开菲乳、泡菜等)。采用选择性分离技术,结合分子分型和表型特征鉴定的方法,分离获得4,500余株不同类型的乳酸菌,以冻干管的方式在-80℃保藏。按照国际规则建立了检索体系,是中国保藏菌株数最多的乳酸菌资源库之一。通过表型特征和分子分型的方法获得了一个新种牛类芽孢菌BD3526 (Paenibacillus bovis sp. nov),并完成国际保藏(CGMCC8333=DSM28815=ATCC00318) ,该菌具有抗糖尿病、调节肠道菌群组成、抑制病原菌对肠道黏附等多种生理活性,具备作为下一代益生菌的潜力。
创新机构全球布局
乳酸菌资源库涵盖了乳杆菌属(Lactobacillus)、链球菌属(Streptococcus)、乳球菌属(Lactococcus)、明串珠菌属(Leuconostoc)、片球菌属(Pediococcus)和双歧杆菌属(Bifidobacterium)等乳品工业所使用的主要种类。同时,通过交换、赠送等方式收藏了50多株标准菌株。